Why No One Cares About ADHD Medication Pregnancy
ADHD Medication During Pregnancy and Breastfeeding
Women with ADHD have to make a difficult choice about whether to continue or stop taking ADHD medication during pregnancy and breast-feeding. There isn't much information on how long-term exposure to these drugs may affect the fetus.
A study recently published in Molecular Psychiatry demonstrates that children exposed to ADHD medication during pregnancy do not develop neurological problems such as hearing loss or vision, febrile seizures, or IQ impairment. The authors acknowledge that more high-quality studies are needed.
Risk/Benefit Analysis
Women who are pregnant and taking ADHD medications need to balance the benefits of taking them against potential risks to the foetus. Doctors don't have the data needed to give clear guidelines but they can provide information regarding benefits and risks that can assist pregnant women in making informed decisions.
A study published in Molecular Psychiatry found that women who were taking ADHD medications during early pregnancy did not face a significantly higher risk of fetal cardiac malformations or major structural birth defects. The researchers used a large, population-based case-control study to assess the risk of major structural birth defects in infants born to mothers who had taken stimulants in early pregnancy, as well as those who had not. Clinical geneticists and pediatric cardiologists looked over the cases to ensure correct case classification and to minimize the possibility of bias.
However, the study was not without its flaws. Researchers were unable in the beginning to distinguish the effects caused by the medication from the disorder. This limitation makes it difficult to know whether the small differences observed in the groups that were exposed are due to the use of medication or confounding by comorbidities. Researchers also did not examine the long-term effects for the offspring.
The study showed that infants whose mothers had taken ADHD medication during pregnancy had a slightly greater risk of being admitted to the neonatal care unit (NICU) as compared to mothers who did not take any medication during pregnancy or had quit taking the medication prior to or during pregnancy. This increase was due to central nervous system-related disorders and the higher risk of admission did not appear to be affected by the type of stimulant medications were taken during pregnancy.
Women who took stimulant ADHD medication during pregnancy were also at an increased risk of having a caesarean section or having a baby born with an low Apgar score (less than 7). These increases appear to be unrelated to the type of medication used during pregnancy.
The researchers suggest that the small risk associated with the use of ADHD medications during early pregnancy could be offset by the higher benefit to both the mother and child of continued treatment for the woman's disorder. Physicians should talk to their patients about this issue and, if possible, help them develop coping skills that could reduce the effects of her disorder on her daily life and relationships.
Medication Interactions
As more women than ever before are being diagnosed with ADHD and being treated with medication, the issue of whether to continue or end treatment during pregnancy is one that more and more doctors confront. Most of the time, these decisions are made in the absence of solid and reliable evidence either way, so physicians must weigh their knowledge about their experiences, the experiences of other doctors, and what the research suggests on the subject, along with their best judgment for each patient.
The issue of potential risks for infants can be particularly tricky. Many of the studies on this issue are based on observations instead of controlled research and their conclusions are often contradictory. Most studies limit their analysis to live births, which can underestimate the teratogenic impact leading to terminations or abortions of pregnancy. The study discussed in the journal club addresses these shortcomings by analyzing both the data from deceased and live births.
Conclusion Some studies have found an association between ADHD medications and certain birth defects, other studies have not shown such a relationship. Most studies show that there is a neutral, or slightly negative, impact. In the end, a careful risk/benefit assessment is required in every situation.
For many women with ADHD who suffer from ADHD, the decision to stop medication can be difficult, if not impossible. In fact, in an article recently published in the Archives of Women's Mental Health psychologist Jennifer Russell notes that stopping ADHD medication during pregnancy can cause depression, feelings of isolation and family conflict for these patients. The loss of medication can also impact the ability to safely drive and complete work-related tasks, which are vital aspects of daily life for those suffering from ADHD.
She suggests that women who are not sure whether to continue taking medication or stop it due to their pregnancy should educate family members, coworkers, and acquaintances about the condition, its impact on daily functioning and the benefits of continuing the current treatment regimen. It can also help women feel supported in her decision. It is important to note that certain medications are able to be absorbed through the placenta so if the patient decides to discontinue her ADHD medication during pregnancy and breastfeeding, she must be aware that the effects of the medication could be transferred to the infant.
Birth Defects and Risk of
As the use of ADHD drugs to treat symptoms of attention deficit hyperactivity disorder (ADHD) grows there are concerns over the impact that these drugs might have on the fetuses. A recent study published in the journal Molecular Psychiatry adds to the existing knowledge on this subject. With two massive data sets researchers were able to analyze more than 4.3 million pregnancies and see whether the use of stimulant medications increased the risk of birth defects. Researchers discovered that although the overall risk is low, first-trimester ADHD medication use was associated with slightly higher risk of specific heart defects like ventriculoseptal defects.
The researchers behind the study found no association between early use of medication and other congenital anomalies, like facial clefting, or club foot. The results are in agreement with previous studies which showed a small, but significant increase in cardiac malformations for women who began taking ADHD medication prior to the birth of their child. This risk increased during the latter part of pregnancy when a large number of women stopped taking their medication.
Women who were taking ADHD medication in the first trimester were more likely to need a caesarean and also have a low Apgar after birth and had a baby that required breathing assistance at birth. The authors of the study were unable to eliminate bias due to selection because they limited their study to women who did not have any other medical conditions that could have contributed to the findings.
The researchers hope their research will aid in the clinical decisions of physicians who see pregnant women. The researchers recommend that, while discussing the risks and benefits are important, the decision on whether to continue or stop medication should be based on the severity of each woman's ADHD symptoms and the needs of the woman.

The authors also caution that, while stopping the medication is an alternative, it is not a recommended practice because of the high incidence of depression and other mental health problems in women who are pregnant or who are recently postpartum. Additionally, adhd in adults medication suggests that women who stop taking their medications will have a tough transitioning to life without them once the baby is born.
Nursing
The responsibilities that come with being a new mom can be overwhelming. Women with ADHD can face severe challenges when they must manage their symptoms, attend doctor appointments and prepare for the birth of a baby and adjust to a new routine. Many women choose to continue taking their ADHD medication during pregnancy.
The risk for nursing infant is low because the majority of stimulant medications is absorbed through breast milk in low amounts. However, the rate of exposure to medication by the newborn can vary depending on dosage, frequency it is administered, and at what time the medication is administered. In addition, various medications enter the baby’s system through the gastrointestinal tract or through breast milk. The impact of these medications on the health of a newborn is not fully known.
Due to the absence of research, some doctors might be tempted to stop taking stimulant medications during a woman's pregnancy. This is a difficult choice for the patient, who must weigh the benefit of continuing her medication against the possible dangers to the embryo. As long as more information is available, GPs can ask pregnant patients if they have any background of ADHD or if they plan to take medication in the perinatal phase.
A growing number of studies have shown that most women can safely continue taking their ADHD medication during pregnancy and breastfeeding. In response, an increasing number of patients are opting to do so. They have discovered after consulting with their physicians, that the benefits of continuing their current medication outweigh any possible risks.
It is essential for women with ADHD who are thinking of breastfeeding to seek out a specialist psychiatrist's advice prior becoming pregnant. They should discuss their medication with their doctor and discuss the pros and cons of continued treatment, including non-pharmacological management strategies. Psychoeducation should also be provided to help pregnant women suffering from ADHD be aware of their symptoms and the root cause and learn about treatments and to reinforce existing strategies for managing. This should include an approach that is multidisciplinary, including the GP, obstetricians and psychiatry. Counselling for pregnancy should include discussion of a management plan for both the mother and child, as well as monitoring for signs of deterioration and, if necessary, adjustments to the medication regimen.